A simple, accurate, precise and specific spectrophotometric method has been developed for the estimation of pirfenidone (PIR) in its tablet dosage form by using methanol as a solvent. The method is calibration graph method which involves estimation of PIR by taking absorbance at 317nm. This method follows Beer’s linearity in the range of 4-28 μg/ml. The mean % recovery was found to be in the range of 99.31–99.86 % for PIR. The proposed method has been validated as per ICH guidelines and successfully applied to the estimation of PIR in its tablet dosage form.
Loading....